There are many wives’ tales and tricks of the trade for helping people to sober up. The truth is, none of these are backed by science, and none of them truly work — so we strongly caution you to not try to use these and drive. Skip the coffee and fatty foods. The only remedy for lowering the concentration of alcohol in your bloodstream is time. However, we can make some suggestions for aiding or avoiding a hangover. Drink lots of water, get plenty of rest, and consider an anti-inflammatory.